Substrates for cell adhesion prepared via active site-directed immobilization of a protein domain.

Abstract

Recent studies in basic cell biology and bioengineering call for model substrates that present active proteins, with control over protein density, pattern, and orientation, to more directly mimic the natural extracellular matrix. Herein we demonstrate a strategy for controlled, irreversible immobilization of a cell adhesion protein domain onto an otherwise… (More)

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