Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli

@inproceedings{Habersetzer2017SubstratetriggeredPS,
  title={Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli},
  author={Johann Habersetzer and Kristoffer Moore and J. T. Cherry and Grant Buchanan and Phillip J. Stansfeld and Tracy Palmer},
  booktitle={Open biology},
  year={2017}
}
The twin-arginine protein transport (Tat) machinery mediates the translocation of folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of plant chloroplasts. The Escherichia coli Tat system comprises TatC and two additional sequence-related proteins, TatA and TatB. The active translocase is assembled on demand, with substrate-binding at a TatABC receptor complex triggering recruitment and assembly of multiple additional copies of TatA; however, the molecular… CONTINUE READING