Substrate specificity and inhibitory study of human airway trypsin-like protease.


Human airway trypsin-like protease (HAT), also referred to as TMPRSS11D, is an important physiological enzyme with the main activity pronounced in an airway. In this work we have described the substrate specificity and selectivity study of the protease, performed by the combinatorial approach. Fluorogenic/chromogenic tetrapeptide library was used for this… (More)
DOI: 10.1016/j.bmc.2010.06.059


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