Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration

@article{Jeffrey1995SubstrateSI,
  title={Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration},
  author={F. M. H. Jeffrey and V. Diczku and A Dean Sherry and Craig Malloy},
  journal={Basic Research in Cardiology},
  year={1995},
  volume={90},
  pages={388-396}
}
A study of substrate selection in the isolated heart was made using13C NMR isotopomer analysis, a method that unequivocally identifies relative substrate utilization. This technique has several advantages over conventional approaches used to study this problem. It detects the labeling of metabolic end-products present in tissue, as opposed to more indirect methods such as measurement of respiratory quotient, arteriovenous differences, or specific activity changes in the added substrate. It also… CONTINUE READING
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13 C Iso - topomer Analysis of Myocardial Substrate Selection in Early Reperfusion After 15 Minutes of Regional Ischemia in the Working Rabbit Heart

  • MA Solomon, Jeffrey FMH, C Storey, AD Sherry, CR Malloy
  • Soc Mag Reson Med
  • 1993

Effect of increasing degrees of ischemic injury on myocardial oxidative metabolism early after reperfusion in isolated rat hearts

  • G Gorge, J ChatelainRSchaper, R Lerch
  • Circ Res
  • 1991

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