Substrate inhibition kinetics in assemblages of cells.

  title={Substrate inhibition kinetics in assemblages of cells.},
  author={Barry J. Bunow and Clark K. Colton},
  journal={Bio Systems},
  volume={7 1},
The collective kinetic behavior of a linear array of cells containing a substrate inhibited enzyme is studied with a model in which each cell is considered a well-stirred compartment surrounded by a semipermeable membrane. At large values of a reaction-permeation modulus, wherein substrate access to interior cells is limited, plots of total reaction rate versus concentration of the external reservoir show sharp projections which correspond to dominant reaction occurring in a pair of… CONTINUE READING