Substrate induction of osteogenesis from marrow-derived mesenchymal precursors.

Abstract

Therapeutic modalities aimed at bone regeneration are increasingly employing extracellular matrix (ECM) constituents to control bone marrow progenitor cell (BMPC) commitment, growth, and differentiation. However, the precise role these ECM elements play during stem cell differentiation remains unclear. (See also Salaszynk et al., Stem Cells Dev 14(6):608… (More)

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