Substrate effects on endothelial cell adherence rates.

  title={Substrate effects on endothelial cell adherence rates.},
  author={W. Jeffrey Scott and Paul Louis Mann},
  journal={ASAIO transactions},
  volume={36 3},
Endothelial cell attachment to a synthetic substrate was studied using an in vitro model system. Attachment rate was defined as the number of tritium-labeled endothelial cells attached to a synthetic substrate after 30 minutes. The surface of the synthetic substrate was chemically modified with either laminin or fibronectin. Labeled endothelial cells attached more rapidly to synthetic substrate, chemically modified with biomolecules, as compared with the untreated substrate controls. Unlabeled… CONTINUE READING