Substrate dependency of neurite outgrowth from adult human chromaffin cells. Inhibitory effects of human brain tissue.


Attempts to treat Parkinson's disease with grafts of chromaffin cells to the caudate nucleus have recently generated considerable interest. However, it is not known whether chromaffin cells can innervate the human central nervous system. We have directly addressed this question by measuring neurite outgrowth in cultures of normal adult human chromaffin… (More)


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