Substrate-attached Glycoproteins Mediating Adhesion of Normal and Virus-transformed Mouse Fibroblasts

@article{Culp1974SubstrateattachedGM,
  title={Substrate-attached Glycoproteins Mediating Adhesion of Normal and Virus-transformed Mouse Fibroblasts},
  author={Lloyd A. Culp},
  journal={The Journal of Cell Biology},
  year={1974},
  volume={63},
  pages={71 - 83}
}
When BALB/c 3T3, simian virus 40 (SV40)-transformed 3T3 (SVT2), and revertant variants of the transformed cells are removed by EGTA treatment from the substrate on which they were grown, they leave behind a layer of glycoprotein which has been characterized biochemically (Terry, A. H. and L. A. Culp. 1974. Biochemistry. 13:414.)-substrate-attached material (SAM). The influence of SAM from normal and from transformed cells on cellular attachment to the substrate, morphology, movement, and growth… CONTINUE READING