Substitution treatment of injecting opioid users for prevention of HIV infection.
@article{Gowing2004SubstitutionTO,
title={Substitution treatment of injecting opioid users for prevention of HIV infection.},
author={Linda R Gowing and M Farrell and Reinhard Bornemann and Robert Ali},
journal={The Cochrane database of systematic reviews},
year={2004},
volume={4},
pages={
CD004145
}
}BACKGROUND
Injecting drug users are vulnerable to infection with HIV and other blood borne viruses as a result of collective use of injecting equipment as well as sexual behaviour.
OBJECTIVES
To assess the effect of oral substitution treatment for opioid dependent injecting drug users on rates of HIV infections, and high risk behaviours.
SEARCH STRATEGY
Multiple electronic databases were searched. Reference lists of retrieved studies, reviews and conference abstracts were handsearched…
174 Citations
Does opioid substitution treatment in prisons reduce injecting-related HIV risk behaviours? A systematic review.
- MedicineAddiction
- 2010
There may be a role for OST in preventing HIV transmission in prisons, but methodologically rigorous research addressing this question specifically is required.
nterventions to prevent HIV and Hepatitis C in people who inject rugs: A review of reviews to assess evidence of effectiveness
- Medicine
- 2014
Review-level evidence indicates that harm reduction interventions can reduce IRB, with evidence strongest for OST and NSP, however, there is comparatively little review- level evidence regarding the effectiveness of these interventions in preventing HCV transmission among PWID.
Harm reduction among injecting drug users - evidence of effectiveness
- Medicine
- 2010
There is sufficient review-level evidence that OST reduces HIV transmission, while the evidence in support of NSPs reducing HIV transmission is more tentative, and for DCRs currently insufficient, and an uneven presence of high-quality review evidence.
Change in injecting behaviour among people treated for hepatitis C virus: The role of intimate partnerships
- Medicine, PsychologyJournal of viral hepatitis
- 2019
Enrolling couples on HCV treatment when partners are sero‐concordant has shown enhanced benefits for reduction in injecting behaviour, and Treating a hard‐to‐reach population for HCV infection is not only possible, but also bears health benefits beyond treatment of HCV alone.
Sex discrepancies in the protective effect of opioid agonist therapy on incident hepatitis C infection.
- Medicine, BiologyClinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2019
Female PWID exposed to OAT are twice as likely as their male counterparts to acquire HCV, and structural and behavioural interventions that target women, including affordable housing and safe injection self-efficacy, are required to bolster the efficacy of OAT in preventing HCV transmission.
The effectiveness of opioid maintenance treatment in prison settings: a systematic review.
- MedicineAddiction
- 2012
OMT presents an opportunity to recruit problem opioid users into treatment, to reduce illicit opioid use and risk behaviours in prison and potentially minimize overdose risks on release, and if liaison with community-based programmes exists, prison OMT facilitates continuity of treatment and longer-term benefits can be achieved.
Drug Treatment as HIV Prevention: A Research Update
- MedicineJournal of acquired immune deficiency syndromes
- 2010
The scientific literature leaves no doubt about the effectiveness of drug treatment as an HIV prevention strategy, as drug users in substance abuse treatment are significantly more likely to achieve sustained viral suppression, making viral transmission less likely.
Systematic review research on needle/syringe programs and opiate substitution programs in low- and middle-income countries.
- MedicineJournal of food and drug analysis
- 2013
Drug Treatment as HIV Prevention Among Women and Girls Who Inject Drugs From a Global Perspective: Progress, Gaps, and Future Directions
- MedicineJournal of acquired immune deficiency syndromes
- 2015
Development and/or implementation of interventions that facilitate women and girls engaging in drug treatment that address their roles within society, work, and family/relationships, and outcome evaluation of these interventions are crucial.
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