Substitution rates in hepatitis delta virus

  title={Substitution rates in hepatitis delta virus},
  author={Julia Krushkal and Wen-Hsiung Li},
  journal={Journal of Molecular Evolution},
Substitution rates were estimated for the coding and noncoding regions of the hepatitis delta virus (HDV). The estimated rates of synonymous substitution in HDV were lower than the rates of substitution at nonsynonymous sites and in the noncoding region. HDV has lower synonymous substitution rates than the hepatitis C virus, though both are RNA viruses. The relatively low rate of synonymous substitution in HDV may be due to a strong preference of G and C nucleotides at third codon positions… CONTINUE READING
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for a smaller data set. In our study, the South American and the Asian isolates formed distinct subtrees. The exception was the two sequences isolated from the Japanese patient

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Highly Influential
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cleotides for the Lebanon strains, and 1,032 nucleotides for the Taiwanese isolate) Table 4. Average substitution rate/site/year for the HDV coding" and noncoding regions estimated by the method

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suggested that the degree of variation of substitution rate may be correlated with the clinical development of viral infection

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