Substitution of the gene for chloroplast RPS16 was assisted by generation of a dual targeting signal.

@article{Ueda2008SubstitutionOT,
  title={Substitution of the gene for chloroplast RPS16 was assisted by generation of a dual targeting signal.},
  author={Minoru Ueda and Tomotaro Nishikawa and Masaru Fujimoto and Hideki Takanashi and Shin-ichi Arimura and Nobuhiro Tsutsumi and Koh-ichi Kadowaki},
  journal={Molecular biology and evolution},
  year={2008},
  volume={25 8},
  pages={1566-75}
}
Organelle (mitochondria and chloroplasts in plants) genomes lost a large number of genes after endosymbiosis occurred. Even after this major gene loss, organelle genomes still lose their own genes, even those that are essential, via gene transfer to the nucleus and gene substitution of either different organelle origin or de novo genes. Gene transfer and substitution events are important processes in the evolution of the eukaryotic cell. Gene loss is an ongoing process in the mitochondria and… CONTINUE READING
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