Substitution of Arginine for Histidine at Position 209 in the a-Subunit of the Human Insulin Receptor

Abstract

Receptors for insulin and epidermal growth factor contain cysteine-rich domains in the extracellular portion of the molecule. Hiszos (insulin receptor numbering system) is 1 of 2 amino acid residues that are identically conserved in the cysteine-rich domains of insulin receptors, epidermal growth factor receptors, and other homologous receptors… (More)

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