Substitution Matrices of Residue Triplets Derived from Protein Blocks


In protein sequence alignment, residue similarity is usually evaluated by substitution matrix, which scores all possible exchanges of one amino acid with another. Several matrices are widely used in sequence alignment, including PAM matrices derived from homologous sequence and BLOSUM matrices derived from aligned segments of BLOCKS. However, most matrices… (More)
DOI: 10.1089/cmb.2008.0035


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