Substituting dietary linoleic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats.

@article{Ghafoorunissa2005SubstitutingDL,
  title={Substituting dietary linoleic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats.},
  author={Ghafoorunissa and Ahamed Ibrahim and Saravanan Natarajan},
  journal={Biochimica et biophysica acta},
  year={2005},
  volume={1733 1},
  pages={
          67-75
        }
}
This study describes the effect of substituting dietary linoleic acid (18:2 n-6) with alpha-linolenic acid (18:3 n-3) on sucrose-induced insulin resistance (IR). Wistar NIN male weanling rats were fed casein based diet containing 22 energy percent (en%) fat with approximately 6, 9 and 7 en% saturated fatty acids (SFA), monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) respectively for 3 months. IR was induced by replacing starch (ST) with sucrose (SU). Blends of… CONTINUE READING

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