Substituent effect of benzaldehydes on tyrosinase inhibition.

  title={Substituent effect of benzaldehydes on tyrosinase inhibition.},
  author={Ken-ichi Nihei and Isao Kubo},
  journal={Plant physiology and biochemistry : PPB},
Benzaldehyde inhibited the oxidation of 4-t-butylcatechol catalyzed by mushroom tyrosinase with an IC50 of 31.0 μM. The inhibition kinetics analyzed by Dixon plot indicated that it acts as a partial noncompetitive inhibitor. Further studies of several benzaldehydes, particularly those having a substitution at C-4, suggested that the partial inhibitory… CONTINUE READING