Substituent constants of azulene.


The ionization constants in water for six 3-substituted azuloic acids were determined spectrophotometrically. Conversion of these physical constants to their pKa values allowed a set of Hammett-type sigma values for the substituents on these acids to be calculated. Determination of partition coefficients for nine 1-substituted azulenes allowed Hansch-type… (More)


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@article{Lichtenwalner1980SubstituentCO, title={Substituent constants of azulene.}, author={Molly Lichtenwalner and Tully J Speaker}, journal={Journal of pharmaceutical sciences}, year={1980}, volume={69 3}, pages={337-9} }