Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord.

@article{Schirmer2009SubstantialEB,
  title={Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord.},
  author={Lucas Vin{\'i}cius Schirmer and Monika Gsell Albert and Armin Buss and Walter J. Schulz-Schaeffer and Jack P. Antel and Wolfgang Br{\"u}ck and Christine Stadelmann},
  journal={Annals of neurology},
  year={2009},
  volume={66 5},
  pages={
          698-704
        }
}
Research in multiple sclerosis (MS) has recently been focusing on the extent of neuroaxonal damage and its contribution to disease outcome. In the present study, we examined spinal cord tissue from 30 clinically well-characterized MS patients. MS, amyotrophic lateral sclerosis (ALS), and control spinal cord tissue were subjected to morphometric analysis and immunohistochemistry for markers of cell damage and regeneration. Data were related to disease duration and age at death. Here, we present… CONTINUE READING
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