Substantia nigra echogenicity is normal in non-extrapyramidal cerebral disorders but increased in Parkinson's disease

@article{Walter2002SubstantiaNE,
  title={Substantia nigra echogenicity is normal in non-extrapyramidal cerebral disorders but increased in Parkinson's disease},
  author={Uwe Walter and Matthias Wittstock and Reiner Benecke and Dirk W. Dressler},
  journal={Journal of Neural Transmission},
  year={2002},
  volume={109},
  pages={191-196}
}
Transcranial sonography (TCS) revealed substantia nigra (SN) hyperechogenicity in idiopathic Parkinson's disease (IPD). To further evaluate specificity of this finding, we examined 30 IPD patients and 30 age-matched subjects with non-extrapyramidal cerebral disorders (NED). All IPD patients showed a SN hyperechogenicity, in 17 it was bilateral and in 13 unilateral. 7 NED patients had a SN hyperechogenicity, in all it was unilateral, confirming previous results in healthy subjects. Bilateral SN… CONTINUE READING

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