Substance P in the ventrolateral medulla oblongata regulates ventilatory responses.

@article{Chen1990SubstancePI,
  title={Substance P in the ventrolateral medulla oblongata regulates ventilatory responses.},
  author={Zuo Bing Chen and Jan Hedner and Th. Hedner},
  journal={Journal of applied physiology},
  year={1990},
  volume={68 6},
  pages={2631-9}
}
Local injection of substance P (SP) into the ventral portion of the nucleus gigantocellularis, nucleus reticularis lateralis, and nucleus retrofacialis of the ventrolateral medulla oblongata (VLM) or direct application on the ventral surface of the medulla oblongata caused marked stimulation of tidal volume (VT) and/or minute ventilation (VE). The ventilatory response to hypoxia was significantly blunted after SP in the VLM but not in the dorsal medulla oblongata (DM) (nucleus tractus… CONTINUE READING