Substance P-immunoreactive sensory nerves in the lower respiratory tract of various mammals including man

  title={Substance P-immunoreactive sensory nerves in the lower respiratory tract of various mammals including man},
  author={Dr. J. M. Lundberg and Tomas G M H{\"o}kfelt and C. -R. Martling and Alois Saria and Carlos Cuello},
  journal={Cell and Tissue Research},
The occurrence and origin of substance P (SP)-immunoreactive (IR) nerves in the lower respiratory tract was studied by means of immunohistochemistry in the guinea-pig, rat, cat and man. In addition, biopsies from human material were also analysed by radioimmunoassay. SP-IR nerves were seen in four principal locations: 1) under or within the lining epithelium, 2) around blood vessels, 3) within the bronchial smooth muscle layer, and 4) around local tracheobronchial ganglion cells. Ligation… CONTINUE READING


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