Substance P and immunoregulation.


Peptides released from peripheral nerve endings in mammals, including the tachykinin substance P (SP) and vasoactive intestinal polypeptide (VIP), are potent mediators of smooth muscle and vascular functions. Significant neurophysiological activities of SP and VIP include the transmission of nociceptive and interneuron excitatory signals, respectively. SP… (More)


Cite this paper

@article{McGillis1987SubstancePA, title={Substance P and immunoregulation.}, author={Joseph P. McGillis and Michele Organist and Denis Payan}, journal={Federation proceedings}, year={1987}, volume={46 1}, pages={196-9} }