Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures.

Abstract

BACKGROUND The safety and antiemetic efficacy of CP-122,721, a novel neurokinin-1 antagonist, was evaluated when administered alone or in combination with ondansetron. METHODS Using a randomized, double-blind, placebo-controlled study design, CP-122,721 was initially compared with placebo and subsequently to ondansetron alone and in combination for… (More)

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Cite this paper

@article{Gesztesi2000SubstanceP, title={Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures.}, author={Zsuzsanna Gesztesi and Phillip E. Scuderi and P. Carr. White and Wendi Wright and Ronald H. Wender and Robert D'Angelo and Linda S Black and Patricia L Dalby and D. Maclean}, journal={Anesthesiology}, year={2000}, volume={93 4}, pages={931-7} }