Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels

Abstract

Substance P is endogenously released in the adult lamprey spinal cord and accelerates the burst frequency of fictive locomotion. This is achieved by multiple effects on interneurons and motoneurons, including an attenuation of calcium currents, potentiation of NMDA currents and reduction of the reciprocal inhibition. While substance P also depolarizes… (More)
DOI: 10.1371/journal.pone.0133136

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Cite this paper

@inproceedings{Prez2015SubstancePD, title={Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels}, author={Carolina Th{\"{o}rn P{\'e}rez and Russell Hill and Sten Grillner and Stuart E. Dryer}, booktitle={PloS one}, year={2015} }