Subregional pathology of the amygdala complex and entorhinal region in surgical specimens from patients with pharmacoresistant temporal lobe epilepsy.

@article{YilmazerHanke2000SubregionalPO,
  title={Subregional pathology of the amygdala complex and entorhinal region in surgical specimens from patients with pharmacoresistant temporal lobe epilepsy.},
  author={Deniz M. Yilmazer-Hanke and Helmut K. Wolf and Johannes Schramm and Christian Erich Elger and Otmar Dieter Wiestler and Ingmar Bl{\"u}mcke},
  journal={Journal of neuropathology and experimental neurology},
  year={2000},
  volume={59 10},
  pages={907-20}
}
The hippocampus, amygdala complex, and entorhinal region represent anatomically linked limbic structures of the mesiotemporal lobe. Chronic seizures and mnestic deficits in patients with pharmacoresistant mesial temporal lobe epilepsy (TLE) appear to correlate with distinct patterns of histopathological alterations in these areas. The complex anatomical organization of the amygdala and entorhinal region, however, render a detailed neuropathological evaluation of surgical specimens difficult. In… CONTINUE READING