Subpopulation of proepicardial cells is derived from the somatic mesoderm in the chick embryo.

@article{Schlueter2013SubpopulationOP,
  title={Subpopulation of proepicardial cells is derived from the somatic mesoderm in the chick embryo.},
  author={Jan Schlueter and Thomas Brand},
  journal={Circulation research},
  year={2013},
  volume={113 10},
  pages={1128-37}
}
RATIONALE The proepicardium (PE) is a transient structure forming at the venous pole of the heart and gives rise to the epicardium, fibroblasts, and smooth muscle cells. The embryological origin of the PE is presently unclear. Asymmetrical formation of the PE on the right inflow tract is a conserved feature of many vertebrate embryos, and in the chicken is under the control of fibroblast growth factor 8 and snail homolog 1. OBJECTIVE To gain further insight into the process of asymmetrical PE… CONTINUE READING
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