Subplate neurons pioneer the first axon pathway from the cerebral cortex.

@article{McConnell1989SubplateNP,
  title={Subplate neurons pioneer the first axon pathway from the cerebral cortex.},
  author={Susan K. McConnell and A. K. Ghosh and Carla J. Shatz},
  journal={Science},
  year={1989},
  volume={245 4921},
  pages={978-82}
}
During the development of the nervous system, growing axons must traverse considerable distances to find their targets. In insects, this problem is solved in part by pioneer neurons, which lay down the first axonal pathways when distances are at a minimum. Here the existence of a similar kind of neuron in the developing mammalian telencephalon is described. These are the subplate cells, the first postmitotic neurons of the cerebral cortex. Axons from subplate neurons traverse the internal… CONTINUE READING
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