Subpial amyloid plaques in the cerebellum in a case of Alzheimer's disease.

@article{Takamatsu1997SubpialAP,
  title={Subpial amyloid plaques in the cerebellum in a case of Alzheimer's disease.},
  author={Junichi Takamatsu and Tomo Kimura and Akira Kondo and Takeshi Iwatsubo},
  journal={Dementia and geriatric cognitive disorders},
  year={1997},
  volume={8 3},
  pages={
          157-62
        }
}
We studied the morphological and immunohistochemical characteristics of subpial amyloid plaques (SAPs), which were found particularly in the cerebellum of an Alzheimer's disease (AD) patient, and compared them to the senile plaques (SPs) and amyloid angiopathy in AD cerebrum. The case presented herein exhibited a variety of amyloid deposition including SAPs and amyloid angiopathy. SAPs were visualized most intensely with antibodies to amyloid-beta protein (A beta), compared with the… CONTINUE READING