Suboptimal effect of different vitamin D3 supplementations and doses adapted to baseline serum 25(OH)D on achieved 25(OH)D levels in patients with a recent fracture: a prospective observational study.

@article{ShabBidar2013SuboptimalEO,
  title={Suboptimal effect of different vitamin D3 supplementations and doses adapted to baseline serum 25(OH)D on achieved 25(OH)D levels in patients with a recent fracture: a prospective observational study.},
  author={S Shab-Bidar and Sandrine P. G. Bours and Piet P. Geusens and Robert Y. van der Velde and Marcel J. W. Janssen and Joop P. W. van den Bergh},
  journal={European journal of endocrinology},
  year={2013},
  volume={169 5},
  pages={
          597-604
        }
}
OBJECTIVE Guidelines on the need for dose adaptation of vitamin D3 supplementation according to baseline serum 25(OH)D are inconclusive. The effects of increasing doses of vitamin D3 at lower baseline serum 25(OH)D values on the serum 25(OH)D after 4.2 and 11 months were determined in an observational study. DESIGN A prospective observational study. METHODS Out of 1481 consecutive women and men with a recent clinical fracture, 707 had a baseline 25(OH)D level <50 nmol/l and were… CONTINUE READING
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