Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis.

@article{Beattie2012SuboptimalDZ,
  title={Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis.},
  author={John H. Beattie and M Grace Gordon and Susan J. Duthie and Chris J. McNeil and Graham W. Horgan and Graeme F. Nixon and Joerg Feldmann and In-Sook Kwun},
  journal={Molecular nutrition & food research},
  year={2012},
  volume={56 7},
  pages={1097-105}
}
SCOPE Cardiovascular health is strongly influenced by diet. Zinc has antioxidant and anti-inflammatory properties but its long-term influence on vascular health at dietary intake levels relevant to the human population in developed countries has not been studied. We investigated the influence of suboptimal zinc intake in a Western-type diet on the development of vascular inflammation and arterial plaque in apoE knock-out (AEKO) mice. METHODS AND RESULTS Weanling AEKO and wild-type (WT… CONTINUE READING