Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.

@article{Stein2000SubnuclearOA,
  title={Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.},
  author={Gary S Stein and Andre J. van Wijnen and Janet L Stein and Jane B Lian and Mart{\'i}n Montecino and K Zaidi and Amjad Javed},
  journal={Journal of cellular biochemistry. Supplement},
  year={2000},
  volume={Suppl 35},
  pages={
          84-92
        }
}
The regulated and regulatory components that interrelate nuclear structure and function must be experimentally established. A formidable challenge is to define further the control of transcription factor targeting to acceptor sites associated with the nuclear matrix. It will be important to determine whether acceptor proteins are associated with a pre-existing core-filament structural lattice or whether a compositely organized scaffold of regulatory factors is dynamically assembled. An… CONTINUE READING

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