Submucosal injection of normal saline may prevent tissue damage from argon plasma coagulation: an experimental study using resected porcine esophagus, stomach, and colon.

@article{Fujishiro2006SubmucosalIO,
  title={Submucosal injection of normal saline may prevent tissue damage from argon plasma coagulation: an experimental study using resected porcine esophagus, stomach, and colon.},
  author={Mitsuhiro Fujishiro and Naohisa Yahagi and Masanori Nakamura and Naomi Kakushima and Shinya Kodashima and Satoshi Ono and Katsuya Kobayashi and Takuhei Hashimoto and Nobutake Yamamichi and Ayako Tateishi and Yasuhito Shimizu and Masashi Oka and Masao Ichinose and Masao Omata},
  journal={Surgical laparoscopy, endoscopy & percutaneous techniques},
  year={2006},
  volume={16 5},
  pages={307-11}
}
Argon plasma coagulation (APC) is considered to be a safe thermocoagulation technique, but some reports show perforation and deformity during and after APC. In this study, we investigated the usefulness of prior submucosal injection for APC. APC over the mucosa was performed on fresh resected porcine esophagus, stomach, and colon with prior submucosal injection of normal saline (injection group) and without it (control group). The depth of tissue damage increased linearly with pulse duration up… CONTINUE READING

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