Subminimal Inhibitory Concentrations of the Disinfectant Benzalkonium Chloride Select for a Tolerant Subpopulation of Escherichia coli with Inheritable Characteristics

Abstract

Exposure of Escherichia coli to a subminimal inhibitory concentration (25% below MIC) of benzalkonium chloride (BC), an antimicrobial membrane-active agent commonly used in medical and food-processing environments, resulted in cell death and changes in cell morphology (filamentation). A small subpopulation (1-5% of the initial population) survived and… (More)
DOI: 10.3390/ijms13044101

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@inproceedings{Moen2012SubminimalIC, title={Subminimal Inhibitory Concentrations of the Disinfectant Benzalkonium Chloride Select for a Tolerant Subpopulation of Escherichia coli with Inheritable Characteristics}, author={Birgitte Moen and Knut Rudi and Erlend Bore and Solveig Langsrud}, booktitle={International journal of molecular sciences}, year={2012} }