Submicron lipid emulsions containing amphipathic polyethylene glycol for use as drug-carriers with prolonged circulation time

@inproceedings{Lundberg1996SubmicronLE,
  title={Submicron lipid emulsions containing amphipathic polyethylene glycol for use as drug-carriers with prolonged circulation time},
  author={Bo K. O. Lundberg and B-C. Mortimer and Trevor G. Redgrave},
  year={1996}
}
Abstract Submicron-sized lipid emulsions possess many favourable properties as drug-carriers like biocompatibility, physical stability and ease of preparation. The use of colloidal carriers is, however, hampered by their rapid clearance from the circulation. In the present study, this problem was tackled by coating the emulsion droplets with polyethylene glycol modified phosphatidylethanolamine (PEG-PE). Physical stability was obtained by using a mixture of phosphatidylcholine and polysorbate… CONTINUE READING

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