Submaximal primary angioplasty for symptomatic intracranial atherosclerosis: peri-procedural complications and long-term outcomes

  title={Submaximal primary angioplasty for symptomatic intracranial atherosclerosis: peri-procedural complications and long-term outcomes},
  author={G. Peng and Jingyu Zhang and Baixue Jia and Ziqi Xu and D. Mo and N. Ma and F. Gao and Z. Miao},
PurposeThe aim of our study is to report the peri-procedural complications and long-term stroke recurrent rate of symptomatic intracranial atherosclerosis (ICAS) patients who underwent submaximal primary angioplasty.MethodsThis is a retrospective analysis of consecutive patients in a single center who underwent submaximal primary angioplasty between January 1, 2012 and December 31, 2015. The peri-procedural complications and long-term outcomes are reported.ResultsPrimary angioplasty was… Expand
4 Citations
Submaximal angioplasty in the treatment of patients with symptomatic ICAD: a systematic review and meta-analysis
It is suggested that SA might be a promising alternative treatment in the treatment of symptomatic ICAD due to its favorable technical profile, periprocedural safety, and long-term efficacy, and a randomized clinical trial is warranted to compare the safety and efficacy of SA with 'gold standard' medical treatment. Expand
Current Advances in Endovascular Treatment of Intracranial Atherosclerotic Disease and Future Prospective.
There exists a lack of consensus regarding the best endovascular treatment approach or management of in-stent restenosis in patients with symptomatic ICAD, and another area of clinical controversy relates to the ideal use and duration of antiplatelet therapy. Expand
Association of residual stenosis after balloon angioplasty with vessel wall geometries in intracranial atherosclerosis
  • Zhikai Hou, Zhe Zhang, +10 authors Ning Ma
  • Medicine
  • Journal of neurointerventional surgery
  • 2021
Background Percutaneous transluminal balloon angioplasty (PTBA) may be an alternative treatment for patients with symptomatic intracranial atherosclerotic disease (ICAD) refractory to medicalExpand
Intracranial Atherosclerosis: A Disease of Functional, not Anatomic Stenosis? How Trans-Stenotic Pressure Gradients Can Help Guide Treatment.
Angiographic stenosis does not reflect the physiologic severity of distal flow limitation in patients with ICAD and Hemodynamic assessment using trans-stenotic pressure ratios and gradients may serve as a more reliable predictive biomarker for MMT failure and response to revascularization. Expand


Primary angioplasty for a subtype of symptomatic middle cerebral artery stenosis
These results suggest that this treatment is safe and could provide a durable clinical result at long-term follow-up in this subtype of patients, but the high rate of dissection remains a major technical drawback. Expand
Reappraisal of Primary Balloon Angioplasty without Stenting for Patients with Symptomatic Middle Cerebral Artery Stenosis
In this retrospective series, balloon angioplasty without stenting was a safe, effective modality for symptomatic MCA stenosis and may offer a better supplemental treatment option for patients refractory to medical therapy. Expand
Balloon Angioplasty for Intracranial Atherosclerotic Disease: Periprocedural Risks and Short-Term Outcomes in a Multicenter Study
Balloon angioplasty is a relatively safe alternative treatment for intracranial atherosclerotic disease and its role in the long-term secondary prevention of recurrent stroke as compared with intrac Cranial stenting and medical therapy remains to be determined. Expand
Angioplasty for Symptomatic Intracranial Stenosis: Clinical Outcome
Intracranial angioplasty can be performed with a high degree of technical success and a low risk of complications and demonstrates a risk of future strokes that compares favorably to patients receiving medical therapy. Expand
Submaximal angioplasty for symptomatic intracranial atherosclerosis: a prospective Phase I study.
This study demonstrates the safety of the submaximal angioplasty technique, with no permanent periprocedural complications in 24 treated patients, demonstrating an alternative and understudied revascularization treatment for ICAD. Expand
Revisiting angioplasty without stenting for symptomatic intracranial atherosclerotic stenosis after the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) study.
Periprocedural safety of submaximal angioplasty in the setting of acute, symptomatic atherosclerotic intracranial stenosis was demonstrated and compares favorably with rates of identically defined event-free survival for patients randomized to the medical and surgical arms of SAMMPRIS despite the absence of aggressive medical management. Expand
Detailed Analysis of Periprocedural Strokes in Patients Undergoing Intracranial Stenting in Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS)
Periprocedural strokes in SAMMPRIS had multiple causes with the most common being perforator occlusion, and excluding patients with these features from undergoing percutaneous transluminal angioplasty and stenting to lower the procedural risk would limit per cutaneous translumsinal angio-stenting and stent selection to a small subset of patients. Expand
Primary Angioplasty Versus Stenting for Endovascular Management of Intracranial Atherosclerotic Disease Following Acute Ischemic Stroke.
The risk of mortality is found to be elevated following angioplasty alone in comparison to revascularization with stent placement, without a corresponding significant difference in iatrogenic stroke rate. Expand
The NIH registry on use of the Wingspan stent for symptomatic70–99% intracranial arterial stenosis
Comparison of the event rates in high-risk patients in Warfarin-Aspirin Symptomatic Intracranial Disease vs this registry do not rule out either that stenting could be associated with a substantial relative risk reduction or has no advantage compared with medical therapy. Expand
Significance of Good Collateral Compensation in Symptomatic Intracranial Atherosclerosis
Good collateral compensations are more important in patients with symptomatic intracranial stenosis and compromised antegrade flow, and are associated with favorable outcome and less recurrence risk, and the feasibility of composite flow assessment should be explored. Expand