Submandibular salivary gland transfer for the prevention of radiation‐induced xerostomia in patients with nasopharyngeal carcinoma: 5‐Year outcomes

@article{Liu2011SubmandibularSG,
  title={Submandibular salivary gland transfer for the prevention of radiation‐induced xerostomia in patients with nasopharyngeal carcinoma: 5‐Year outcomes},
  author={Xuekui Liu and Yong Su and Naresh Jha and Ming-Huan Hong and Hai-Qiang Mai and Wei Fan and Zong-yuan Zeng and Zhu-ming Guo},
  journal={Head \& Neck},
  year={2011},
  volume={33}
}
Our aim in this study was to investigate the value of the submandibular salivary gland transfer procedure in prevention of radiation‐induced xerostomia in patients with nasopharyngeal carcinoma (NPC). 
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Combination of submandibular salivary gland transfer and intensity‐modulated radiotherapy to reduce dryness of mouth (xerostomia) in patients with head and neck cancer
TLDR
Combining surgical submandibular‐gland transfer with intensity‐modulated radiotherapy (IMRT) may provide greater protection of salivary function in patients with Xerostomia.
Implementation of submandibular gland transfer: A multi‐institutional study of feasibility and time to treatment
Submandibular gland transfer (SMGT) mitigates radiation‐induced xerostomia but has yet to be widely adopted. We evaluate the feasibility of incorporating SMGT at multiple academic institutions and…
Two‐stage autotransplantation of the human submandibular gland: First long‐term results
TLDR
This study investigates long‐term results of a new surgical method that spares the submandibular gland from radiation in patients with radiotherapy-related Xerostomia.
Safety of contralateral submandibular gland sparing in locally advanced oropharyngeal cancers: A multicenter review
TLDR
A large cohort of patients with locally advanced head and neck cancer that underwent contralateral submandibular gland‐sparing radiotherapy is presented, to demonstrate feasibility and safety specifically in patients with local advanced disease.
Submandibular Gland Transfer for the Prevention of Postradiation Xerostomia in Patients with Head and Neck Cancer: A Systematic Review and Meta-Analysis
TLDR
The present clinical evidence suggests that submandibular gland transfer might be highly effective to prevent postradiation xerostomia in head-and-neck cancers without serious adverse events, but more randomized controlled trials are still needed to confirm this conclusion.
A phase II study of submandibular gland transfer prior to radiation for prevention of radiation-induced xerostomia in head-and-neck cancer (RTOG 0244).
Management of Dysphagia Following Radiotherapy
TLDR
This chapter will give an overview of the management of dysphagia related to RT or CRT in the Management of head and neck cancers.
Two-stage autotransplantation of human submandibular gland: a novel approach to treat postradiogenic xerostomia
TLDR
Following two-stage autotransplantation of the submandibular gland, xerostomia in the patients was markedly reduced due to improved saliva production of the reimplanted gland, whether this promising novel approach is a reliable treatment option for RT patients in general should be evaluated in further studies.
Development of Human Salivary Gland-Like Tissue In Vitro.
The loss of salivary gland function caused by radiation therapy of the head and neck is a serious condition and it affects a patient's quality of life. The current lack of effective therapies deman...
Submandibular gland transfer for the prevention of radiation-induced xerostomia in oropharyngeal cancer: Dosimetric impact in the intensity modulated radiotherapy era.
BACKGROUND Submandibular gland (SMG) transfer decreased radiation-associated xerostomia in the 2/3-dimensional radiotherapy era. We evaluated the dosimetric implications of SMG transfer on modern…
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References

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TLDR
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TLDR
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