Sublytic complement injury does not activate NF-kappa B, or induce mitogenesis in rat mesangial cells.

Abstract

Sublytic complement injury to glomerular mesangial cells, mediated by the terminal membrane attack complex of complement (C5b-9), is a potential initiating mechanism in IgA nephropathy. Sublytic complement injury has been reported to result in the production of a variety of pro-inflammatory molecules and growth factors, including many regulated by the… (More)

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@article{Mudge2000SublyticCI, title={Sublytic complement injury does not activate NF-kappa B, or induce mitogenesis in rat mesangial cells.}, author={Suzie Mudge and Jennifer L. McRae and Russell B Auwardt and Brian Murphy and Cheng-fu Chen and Desmond Power}, journal={Experimental nephrology}, year={2000}, volume={8 4-5}, pages={291-8} }