Subject-based reference values: biological variation, individuality, and reference change values.

@article{Walton2012SubjectbasedRV,
  title={Subject-based reference values: biological variation, individuality, and reference change values.},
  author={Raquel M. Walton},
  journal={Veterinary clinical pathology},
  year={2012},
  volume={41 2},
  pages={175-81}
}
Subject-based reference values have been largely overlooked in veterinary medicine. These values represent longitudinal data rather than the cross-sectional data represented by standard population-based reference values. As such they provide information about biological and analytical variation. Inherent random variation of analytes around a homeostatic set point is referred to as biological variation; data on biological variation are underutilized in veterinary medicine and have multiple… CONTINUE READING