Subgingival microbial profiles of smokers with periodontitis.

@article{Shchipkova2010SubgingivalMP,
  title={Subgingival microbial profiles of smokers with periodontitis.},
  author={A Y Shchipkova and Haikady N. Nagaraja and Purnima S Kumar},
  journal={Journal of dental research},
  year={2010},
  volume={89 11},
  pages={1247-53}
}
The subgingival microbiome is largely uncultivated, and therefore, cultivation-based and targeted molecular approaches have limited value in examining the effect of smoking on this community. We tested the hypothesis that the subgingival biofilm is compositionally different in current and never-smokers by using an open-ended molecular approach for bacterial identification. Subgingival plaque from deep sites of current and never-smokers matched for disease was analyzed by 16S sequencing. Smokers… CONTINUE READING

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