Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

  title={Subendothelial retention of atherogenic lipoproteins in early atherosclerosis},
  author={Kristina Sk{\aa}l{\'e}n and Maria Gustafsson and Ellen Knutsen Rydberg and Lillemor Mattsson Hult{\'e}n and Olov Wiklund and Thomas L. Innerarity and Jan Bor{\'e}n},
Complications of atherosclerosis are the most common cause of death in Western societies. Among the many risk factors identified by epidemiological studies, only elevated levels of lipoproteins containing apolipoprotein (apo) B can drive the development of atherosclerosis in humans and experimental animals even in the absence of other risk factors. However, the mechanisms that lead to atherosclerosis are still poorly understood. We tested the hypothesis that the subendothelial retention of… CONTINUE READING
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