Subdivisions of primary motor cortex based on cortico-motoneuronal cells.

  title={Subdivisions of primary motor cortex based on cortico-motoneuronal cells.},
  author={Jean-Alban Rathelot and Peter Strick},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={106 3},
We used retrograde transneuronal transport of rabies virus from single muscles of rhesus monkeys to identify cortico-motoneuronal (CM) cells in the primary motor cortex (M1) that make monosynaptic connections with motoneurons innervating shoulder, elbow, and finger muscles. We found that M1 has 2 subdivisions. A rostral region lacks CM cells and represents an "old" M1 that is the standard for many mammals. The descending commands mediated by corticospinal efferents from old M1 must use the… CONTINUE READING
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