Subdivision of S-phase and its use for comparative purposes in cultured human cells.

@article{Savage1984SubdivisionOS,
  title={Subdivision of S-phase and its use for comparative purposes in cultured human cells.},
  author={John R. K. Savage and Rajendra Prasad and D. G. Papworth},
  journal={Journal of theoretical biology},
  year={1984},
  volume={111 2},
  pages={355-67}
}
Intranuclear DNA synthesis and concomitant chromosome duplication occur during a discrete period of the cell cycle termed S-phase. Using replication-banding and serial time sampling in asynchronous cell populations, it is possible to subdivide the S-phase into four or five chronological compartments termed "subphases". This paper discusses methods for analysing the sampling data to obtain the average duration of these subphases and the positions within S of the borders between them. Such… CONTINUE READING