Subdiaphragmatic vagotomy fails to inhibit intravenous leptin-induced IL-1beta expression in the hypothalamus.

Abstract

Leptin is known to be an important circulating signal for regulation of food intake and body weight. Recent evidence has suggested that leptin is involved in infection and inflammation. The afferent vagus nerve is known to be an important component for transmitting peripheral immune signals to the brain, such as interleukin (IL)-1beta expression in the… (More)

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@article{Hosoi2002SubdiaphragmaticVF, title={Subdiaphragmatic vagotomy fails to inhibit intravenous leptin-induced IL-1beta expression in the hypothalamus.}, author={Toru Hosoi and Yasunobu Okuma and Atsushi Ono and Y Nomura}, journal={American journal of physiology. Regulatory, integrative and comparative physiology}, year={2002}, volume={282 2}, pages={R627-31} }