Subcutaneous panniculitis-like T-cell lymphoma: successful initial treatment with prednisolone and cyclosporin A.

Abstract

A case of subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is reported. A 27-year-old man presented with fever and abdominal swelling. His laboratory examination revealed pancytopenia and liver dysfunction. The diagnosis of SPTCL was made by biopsy based on thickened subcutaneous tissue. In addition, bone marrow specimen showed a hemophagocytosis syndrome (HPS). Methylprednisolone pulse therapy was initiated followed by prednisolone (60 mg/day) and cyclosporin A (150 mg/day). He responded to the treatment and remained asymptomatic for at least for 6 months. Our results suggest that a trial of cyclosporin A is warranted in patients with SPTCL complicated by HPS.

Cite this paper

@article{Tsukamoto2006SubcutaneousPT, title={Subcutaneous panniculitis-like T-cell lymphoma: successful initial treatment with prednisolone and cyclosporin A.}, author={Yuka Tsukamoto and Yoshioka Katsunobu and Yoko Omura and Isseki Maeda and Manabu Hirai and Hirofumi Teshima and Yoshio Konishi and Takeshi Inoue and Toshihiko Sato}, journal={Internal medicine}, year={2006}, volume={45 1}, pages={21-4} }