Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: a systematic review and indirect comparison.

@article{Dretzke2013SubcutaneousAS,
  title={Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: a systematic review and indirect comparison.},
  author={Janine Dretzke and Angela Meadows and Nicola Novielli and Aarnoud Huissoon and Anne Fry-Smith and Catherine A Meads},
  journal={The Journal of allergy and clinical immunology},
  year={2013},
  volume={131 5},
  pages={1361-6}
}
BACKGROUND Severe allergic rhinitis uncontrolled by pharmacotherapy can adversely affect quality of life. Both subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) have demonstrated effectiveness in this patient group; however, it remains uncertain which route of administration is more effective. OBJECTIVES We sought to update existing systematic reviews on the clinical effectiveness of SCIT and SLIT versus placebo, to undertake a systematic review of head-to-head trials, and… CONTINUE READING
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