Subcutaneous adipose tissue transplantation in diet-induced obese mice attenuates metabolic dysregulation while removal exacerbates it

@inproceedings{Foster2013SubcutaneousAT,
  title={Subcutaneous adipose tissue transplantation in diet-induced obese mice attenuates metabolic dysregulation while removal exacerbates it},
  author={Michelle T. Foster and Samir Softic and Jody L. Caldwell and Rohit Kohli and Annette D deKloet and Randy J Seeley},
  booktitle={Physiological reports},
  year={2013}
}
Adipose tissue distribution is an important determinant of obesity-related comorbidities. It is well established that central obesity (visceral adipose tissue accumulation) is a risk factor for many adverse health consequences such as dyslipidemia, insulin resistance and type-2-diabetes. We hypothesize that the metabolic dysregulation that occurs following high fat diet-induced increases in adiposity are due to alterations in visceral adipose tissue function which influence lipid flux to the… CONTINUE READING

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