Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury.

@article{Wu2004SubcorticalWM,
  title={Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury.},
  author={Hsiao-Ming Wu and Sung-Cheng Huang and Naoya Hattori and Thomas C. Glenn and Paul M. Vespa and David A. Hovda and Marvin Bergsneider},
  journal={Neurosurgery},
  year={2004},
  volume={55 6},
  pages={1306-15; discussio 1316-7}
}
OBJECTIVE We used positron emission tomographic studies to prospectively examine the relationship between glucose and oxidative metabolism in the subcortical white matter (WM) acutely after traumatic brain injury (TBI). The objective was to determine the nature, extent, and degree of metabolic abnormalities in subcortical brain regions remote from hemorrhagic lesions. METHODS Sixteen normal volunteers and 10 TBI patients (Glasgow Coma Scale score, 4-10; age, 17-64 yr; 6 with focal and 4 with… CONTINUE READING

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