Subcortical volume analysis in traumatic brain injury: The importance of the fronto-striato-thalamic circuit in task switching

@article{Leunissen2014SubcorticalVA,
  title={Subcortical volume analysis in traumatic brain injury: The importance of the fronto-striato-thalamic circuit in task switching},
  author={Inge Leunissen and James P. Coxon and Karen Caeyenberghs and Karla Michiels and Stephan P. Swinnen},
  journal={Cortex},
  year={2014},
  volume={51},
  pages={67-81}
}
Traumatic brain injury (TBI) is associated with neuronal loss, diffuse axonal injury and executive dysfunction. Whereas executive dysfunction has traditionally been associated with prefrontal lesions, ample evidence suggests that those functions requiring behavioral flexibility critically depend on the interaction between frontal cortex, basal ganglia and thalamus. To test whether structural integrity of this fronto-striato-thalamic circuit can account for executive impairments in TBI we… CONTINUE READING

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