Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression
@article{Lawrence2004SubcorticalAV, title={Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression}, author={N. Lawrence and A. Williams and S. Surguladze and V. Giampietro and M. Phillips}, journal={Biological Psychiatry}, year={2004}, volume={55}, pages={578-587} }
BACKGROUND
Bipolar disorder (BD) is characterised by abnormalities in mood and emotional processing, but the neural correlates of these, their relationship to depressive symptoms, and the similarities with deficits in major depressive disorder (MDD) remain unclear. We compared responses within subcortical and prefrontal cortical regions to emotionally salient material in patients with BP and MDD using functional magnetic resonance imaging.
METHODS
We measured neural responses to mild and… CONTINUE READING
Topics from this paper
Paper Mentions
Interventional Clinical Trial
The proposed 3-week, double-blind, crossover, proof of concept study aims to manipulate
neurochemical dysfunctions characteristic of individuals with co-occurring BD and AUD (i.e… Expand
Conditions | Alcohol Use Disorder, Bipolar Disorder |
---|---|
Intervention | Drug |
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