Subcortical and Neocortical Guidance of Area-specific Thalamic Innervation

  title={Subcortical and Neocortical Guidance of Area-specific Thalamic Innervation},
  author={Tomomi Shimogori and Elizabeth A Grove},
The specialized functions of neocortical areas depend on patterned innervation from the thalamus. Recent evidence suggests several key molecules for correct connections of thalamocortical axons (TCAs) between specific thalamic nuclei and cortical areas. First, the correct area map has to be generated in cortex, and thalamic nuclei need to be specified in correct patterns. Second, axon guidance molecules that are expressed in the TCA subcortical pathway need to be established. Finally, guidance… CONTINUE READING

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